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Boca Biolistics Reference Laboratory > Test Menu > H > HSV 1/2

HSV 1/2

Abbreviation

HSV12

Preferred Specimen

Anogenital lesion swab specimens collected with the MSwab Collection, Transport and Preservation System

Collection Instructions

Mswab Collection system

Transport Temperature

Ambient

Stability

Anogenital lesion swab specimens collected with the MSwab Collection, Transport and Preservation System are stable for transport and storage at 2-30°C for 4 days, or 2-8°C for 14 days, and frozen at -20°C for 90 days

Methodology

  • Automated sample preparation to extract nucleic acids from the anogenital lesion specimens.
  • PCR amplification of target DNA sequences using HSV-1 and HSV-2 specific primers, and real-time detection of cleaved fluorescent-labeled HSV-1 and HSV-2 specific oligonucleotide detection probes.

Reference Ranges

  • HSV 1 Neg/HSV 2 Neg
  • HSV 1 Pos/ HSV 2 Neg
  • HSV 1 Neg/ HSV 2 Pos
  • HSV 1 Pos/ HSV 2 Pos
  • HSV 1 Invalid/HSV 2 Invalid

Clinical Significance

Utilizes real-time polymerase chain reaction (PCR), for the direct detection and differentiation of Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) DNA in clinician-collected, external anogenital lesion specimens from symptomatic male and female patients. The cobas® HSV 1 and 2 Test is intended for use as an aid in diagnosis of anogenital HSV-1 and HSV-2 infections in symptomatic patients.

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