IGF-1

Abbreviation

IGF1

Preferred Specimen

Serum

Minimum Volume

0.5mL

Collection Instructions

Routine Venipuncture

Transport Container

Draw tube or plastic pour off tube

Transport Temperature

Frozen

Stability

If sample is not being tested same day of draw, separate and freeze at -20C

Methodology

CLIA (Chemiluminescent Immunoassay)

Clinical Significance

  • Low IGF-I values: children with GH deficiency or hypopituitarism, and who have craniopharyngioma.
  • Elevated levels: patients with acromegaly and children with gigantism due to excess of pituitary GH. Puberty, pregnancy, and rare diseases characterized by inability to make or respond to IGF-I produce a distinctive type of growth failure termed Laron dwarfism.

Alternative Names

Insulin-Like Growth Factor 1