Progesterone

Abbreviation

PGN

Preferred Specimen

Serum

Minimum Volume

0.5mL

Collection Instructions

Routine Venipuncture

Transport Container

Draw tube or plastic pour off tube

Transport Temperature

2-8 C (ice packs)

Stability

  • 2-8 C = 5 days
  • -20C = 1 year

Methodology

CLIA (Chemiluminescent Immunoassay)

Reference Ranges

Men:

  • 0.17-0.61 ng/mL

Women:

  • Follicular phase= <0.17-2.7 ng/mL
  • Luteal phase- 2.2-16.1 ng/mL
  • Mid-Luteal phase= 4.0-17.1 ng/mL
  • Post menopausal= <0.17-0.34 ng/mL

Pregnant women:

  • First Trimester= 4.0-26.1 ng/mL
  • Second trimester= 13.8-118 ng/mL
  • Third trimester= 34.2-254 ng/mL

Clinical Significance

Levels are measured in order to monitor ovulation for in vitro fertilization (IVF) and to predict IVF success. In cases of infertility, low Progesterone levels can indicate a defective luteal phase. In early pregnancy, low progesterone levels point to an increased risk of pregnancy loss.